Photo By – Imagn Images. Minnesota Vikings wide receiver Justin Jefferson and Los Angeles Chargers quarterback Justin Herbert are the stars of tonight’s matchup.
The Week 8 installment of Thursday Night Football showcases two teams vying for playoff spots, with the Los Angeles Chargers hosting the Minnesota Vikings.
Although the Chargers have lost three of their last four games, they are still favored by three points, with a total set at 44.5.
Tonight’s Vikings vs. Chargers predictions suggest that a strong Vikings offense could take advantage of a weakened Chargers defense.
Kickoff is scheduled for 8:15 p.m. ET at SoFi Stadium in Inglewood, airing on Prime Video.
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Vikings vs Chargers prediction
Vikings vs Chargers Best bet: Vikings team total Over 20.5 (-112)
The Los Angeles Chargers have been escaping scrutiny for their poor performance, but their defense has been subpar.
In their last three matches, they rank last in the NFL for yards allowed per play, with the Commanders, Dolphins, and Colts all scoring at least 27 points against them.
The game against the Colts was particularly troubling; Indianapolis scored 38 points against the Chargers in only three quarters. They were overpowered both in the air and on the ground, with the Colts scoring touchdowns on four of five red-zone attempts.
Pass defense issues have been escalating for Los Angeles, which has allowed an average of 7.6 yards per pass attempt over their last three games, ranking sixth-worst in the league.
The Minnesota Vikings are poised to capitalize on this shaky pass defense. Carson Wentz has thrown for over 300 yards in two of his last three games, while Justin Jefferson has recorded over 100 yards in two of his last three outings.
Vikings vs Chargers TNF same-game parlay
Expecting both teams to easily surpass 15 points is reasonable.
The Vikings’ chances of winning hinge on their passing game against a struggling defense, with Wentz averaging 299.6 passing yards in his past three games.
Additionally, the Vikings’ pass rush, which is ranked second in the NFL for pressure rate, should enable them to keep control of the game.
Vikings vs Chargers SGP (+595)
- Vikings moneyline (+145)
- Both teams to score 15+ points (-195)
- Carson Wentz Over 222.5 passing yards (-114)
Our big-ticket SGP: Justin Jefferson Airplane
Jefferson is proving to be a top-tier NFL receiver, recording totals of 126, 123, and 79 yards in his last three games, consistently receiving over ten targets in each.
With the Vikings passing at the third-highest rate lately, these trends are likely to continue.
Vikings vs Chargers SGP (+1240)
- Vikings moneyline (+145)
- Both teams to score 15+ points (-195)
- Carson Wentz Over 222.5 passing yards (-114)
- Justin Jefferson Over 75.5 receiving yards (-118)
Vikings vs Chargers game predictions
Vikings vs Chargers moneyline prediction
With the Chargers struggling and revealing significant weaknesses on both ends, this is a ripe moment for an upset pick.
I’ll back the Vikings, who have shown resilience after losses this season.
Vikings vs Chargers spread prediction
The current form of the Chargers suggests they might not be a strong team right now.
While uncertainty remains about the Vikings, I believe they hold an advantage on both sides of the ball, making the points favorable.
Vikings vs Chargers Over/Under prediction
Though Chargers’ defensive flaws are evident, the Vikings have also struggled defensively, ranking 27th in yards allowed over their last three games.
With two aggressive passing offenses on the field, this game appears poised to go Over.
Vikings vs Chargers odds
- Spread: Minnesota +3 (-110) | Los Angeles -4 (-110)
- Moneyline: Minnesota +155 | Los Angeles -185
- Over/Under: Over 44.5 (-110) | Under 44.5 (-110)
Vikings vs Chargers betting trend to know
Los Angeles has hit the 3Q game total Over in 15 of its last 19 games (+10.15 Units / 45% ROI). Find more NFL betting trends for Vikings vs. Chargers.
How to watch Vikings vs Chargers
| Location | SoFi Stadium, Inglewood, CA |
| Date | Thursday, October 23, 2025 |
| Kickoff | 8:15 p.m. ET |
| TV | Amazon Prime |
Learn how to live stream Vikings vs. Chargers for free tonight.
Vikings vs Chargers latest injuries
Vikings vs Chargers weather
The evening weather in Southern California is expected to be mild, with daytime temperatures around 72°F cooling to the upper 50s at night, under mostly clear to partly cloudy skies.
No rain is anticipated, making it comfortable for players and spectators.
SoFi Stadium’s unique open-air design can allow breezes to flow through, potentially affecting field goals, punts, and deeper passes more significantly than in a fully enclosed venue.
Even though the stadium has a cover, it can still be classified as open-air and has experienced weather-related delays in the past due to its design.
As a result, special teams may be more impacted by light winds, although quarterbacks should find good throwing conditions with cool, dry air aiding fast play.
Check for real-time conditions with our live NFL weather info and find out how weather affects NFL betting.
More Thursday Night Football picks from Covers
Odds are accurate at the time of publishing and may change.
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