Published May 14, 2025 • 4 hrs ago
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The NFL will release its complete schedule for the 2025 season tonight at 5:00 p.m. PT. As is usual, some matchups have leaked prior to the official announcement. This tracker consolidates those early reports leading up to the schedule’s full release.
The San Francisco 49ers are set to play each NFC West opponent twice. Additionally, they will compete against the last-place teams from the NFC North (Bears), NFC East (Giants), and AFC North (Browns). Their schedule will also include games against all teams in the NFC South and AFC South.
RELATED 49ers are rumored to kick off the 2025 season on the road against the Seahawks
The NFL season begins on Thursday, September 4, with the Super Bowl champion Philadelphia Eagles taking on the Dallas Cowboys at Lincoln Financial Field. The season will close with Super Bowl LX on February 8, 2026, at Levi’s Stadium in Santa Clara, California, which is the 49ers’ home field.
San Francisco won’t participate in any international games this season since those matchups have already been announced by the NFL. They will also not have games on Thanksgiving or Christmas.
Confirmed or Reported 49ers Games
- Week 1: at Seahawks (Sep. 7, per Dave Mahler)
- Week 2:
- Week 3: vs. Cardinals (Sep. 21, 1:25 p.m., Unconfirmed)
- Week 4: vs. Jaguars (per Dilla, Bold Take Pod)
- Week 5: at Rams (Oct. 2, 5:15 p.m., TNF, @OzzyNFL)
- Week 6:
- Week 7: vs. Falcons (Oct. 19, 5:20 p.m., SNF, Unconfirmed)
- Week 8:
- Week 9: at Giants (Nov. 2, per Art Stapleton)
- Week 10: vs. Rams (Nov. 9, 1:25 p.m., @OzzyNFL)
- Week 11:
- Week 12: vs. Panthers (Nov. 24, 5:15 p.m., MNF, Travis Hancock)
- Week 13:
- Week 14:
- Week 15: vs. Titans (Dec. 14, 1:25 p.m., Unconfirmed)
- Week 16:
- Week 17:
- Week 18: vs. Seahawks (Jan. 3 or 4, Corbin K. Smith)
Note: Unconfirmed listings are speculative until confirmed by an official media member.
Home/Away Opponents
Here are all of the 49ers’ home and away opponents for the 2025 season. Reported matchups are indicated with a strikethrough.
Home (8)
Arizona CardinalsLos Angeles RamsSeattle SeahawksAtlanta FalconsCarolina Panthers- Chicago Bears
Jacksonville JaguarsTennessee Titans
Away (9)
- Arizona Cardinals
Los Angeles RamsSeattle Seahawks- Cleveland Browns
- Houston Texans
- Indianapolis Colts
- New Orleans Saints
New York Giants- Tampa Bay Buccaneers
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