The Grand Canyon Antelopes will face off against the Maryland Terrapins in the NCAA Tournament, with the game slated to begin at 4:35 p.m. ET on TBS.
Maryland enters the matchup as 10.5-point favorites with a moneyline of -600. The game’s total is set at 150.5 points.
Below are my predictions for Grand Canyon vs. Maryland and my college basketball picks for March 21, 2025.
Prediction for Grand Canyon vs Maryland
My Pick: Grand Canyon +10.5 (Play to +10)
I believe the Antelopes will manage to cover the spread, with the most favorable odds currently offered at DraftKings. To ensure you are getting the best lines available for college basketball bets, check out our live NCAAB odds page.
Odds for Grand Canyon vs Maryland
| Grand Canyon Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
|
+10.5 -110 |
150.5 -105o / -115u |
+440 |
| Maryland Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
|
-10.5 -110 |
150.5 -105o / -115u |
-600 |
- Spread: Maryland -10.5
- Over/Under: 150.5 points
- Moneyline: Maryland -600, Grand Canyon +440
- Best Bet: Grand Canyon +10.5 (Play to +10)
Spread Analysis
I think the best bet for this opening NCAA Tournament game is for Grand Canyon to cover the spread.
Moneyline Consideration
While I’m backing the Antelopes on the spread, I’m opting out of the moneyline for this game.
Over/Under Insights
I do not have a recommendation for the total points in this Friday afternoon encounter.
My Pick: Grand Canyon +10.5 (Play to +10)
Betting Preview for Grand Canyon vs Maryland
The showdown between the Grand Canyon Antelopes and the Maryland Terrapins will take place in Seattle, Washington. The Lopes emerged as champions of the WAC after triumphing over Utah Valley in the conference championship.
Grand Canyon gained attention during last year’s NCAA Tournament by defeating Saint Mary’s in the first round. The team retains many players from that squad, although they are missing key contributor Gabe McGlothan.
The absence of McGlothan could pose challenges against a strong Maryland team, known for its impressive talent including standout freshman Derik Queen.
Despite being 10.5-point favorites, I’m hesitant to place that much faith in Maryland. The Lopes may not be as offensively potent as last season but show significant improvement defensively.
Grand Canyon ranks 67th in adjusted defensive efficiency, while excelling at limiting opponent 2-point percentages, holding the 24th spot in that metric. They’re also equipped with considerable size, making them less vulnerable than typical mid-major teams.
Though Maryland is strong, they lack depth, which could become a critical factor if they encounter foul troubles in this matchup.
