Has your 2025 NCAA Tournament bracket already collapsed? The first-round games on Thursday might have derailed your hopes for a flawless bracket, but there are still chances to succeed. Our experts are ready to provide their insights as the first round progresses.
Friday’s games will spotlight the other top No. 1 seeds: Duke in the East Region and Florida in the West Region. Additionally, North Carolina will aim to advance after their contentious selection as the final team in the tournament. Expect non-stop action from noon until the early hours, and check out our top betting suggestions to enhance your viewing experience.
2025 NCAA Tournament bracket forecasts: March Madness expert choices, potential upsets, expected winners, favorites to win
Kyle Boone
Odds are based on consensus from SportsLine | All times are in Eastern
Top betting picks for Friday’s NCAA Tournament first-round matchups
(6) Ole Miss vs. (11) North Carolina
4:05 p.m. on TNT | March Madness Live: North Carolina enters this game with momentum after a strong victory over San Diego State. They face Ole Miss, whose top-30 defense may be challenged by UNC’s dynamic perimeter plays. Given their recent form, including a 9-1 record against the spread in their last ten games, the Tar Heels seem poised to win. Pick: North Carolina -1.5
(7) Marquette vs. (10) New Mexico
7:25 p.m. on TBS | March Madness Live: Marquette has struggled recently, finishing the season with a disappointing record of 1-3 straight up and 0-4 against the spread. New Mexico features standout guard Donovan Dent, who will be pivotal in this matchup. The outcome may hinge on who controls the game tempo, with New Mexico’s size providing an advantage. Pick: New Mexico +3.5
(8) UConn vs. (9) Oklahoma
9:25 p.m. on TNT | March Madness Live: UConn’s defense hasn’t matched its past championship levels, presenting an opening for Oklahoma to capitalize, especially with their talented freshman guard Jeremiah Fears leading the charge. Given UConn’s issues and Oklahoma’s offensive potential, this could result in a high-scoring game. Pick: Over 147.5
(5) Oregon vs. (12) Liberty
10:10 p.m. on TruTV | March Madness Live: With a proven track record of success in postseason play, Oregon’s coach Dana Altman has seen his teams win at least one game in every tournament since his arrival. Facing Liberty, who has struggled against bigger teams, Oregon could create significant advantages with their scoring capabilities. Pick: Oregon -7.5
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